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Table 2 Cox regression analyses of the association between ILSBPD and all-cause and cardiovascular mortality

From: Inter-leg systolic blood pressure difference has been associated with all-cause and cardiovascular mortality: analysis of NHANES 1999–2004

Model

Hazard ratio (95% confidence interval), p value

Inter-leg systolic blood pressure, mmHg

Continuous (per 5mmHg)

Groups

Group 1

(< 5)

Group 2

(5 -< 10)

Group 3

(10 -< 15)

Group 4

(≥ 15)

p for trend

All-cause mortality

Deaths, No. /total, No. (%)

2544/6842 (37.2)

905/2996 (30.2)

709/1928 (36.8)

373/935 (39.9)

557/983 (56.7)

 

Model 1 *

1.16 (1.15, 1.18), p < 0.001

ref

1.27 (1.16, 1.41), p < 0.001

2.39 (2.15, 2.66), p < 0.001

3.37 (2.76, 4.11), p < 0.001

p < 0.001

Model 2 †

1.06 (1.04, 1.08), p < 0.001

ref

1.09 (0.99, 1.21), p = 0.0791

1.04 (0.92, 1.18), p = 0.4904

1.38 (1.24, 1.54), p < 0.001

p < 0.001

Model 3 ‡

1.05 (1.03, 1.07), p < 0.001

ref

1.05 (0.94, 1.18), p = 0.3674

1.03 (0.90, 1.19), p = 0.6749

1.34 (1.18, 1.52), p < 0.001

p < 0.001

Cardiovascular mortality

Deaths, No. /total, No.

648/6842 (9.5%)

209/2996 (7.0%)

171/1928 (8.9%)

87/935 (9.3%)

181/983 (18.4%)

 

Model 1 *

1.20 (1.17, 1.24), p < 0.001

ref

1.33 (1.09, 1.63), p = 0.006

1.41 (1.10, 1.81), p = 0.007

3.37 (2.76, 4.11), p < 0.001

p < 0.001

Model 2 †

1.09 (1.06, 1.12), p < 0.001

ref

1.13 (0.92, 1.38), p = 0.246

1.02 (0.79, 1.31), p = 0.890

1.83 (1.49, 2.24), p < 0.001

p < 0.001

Model 3 ‡

1.07 (1.04, 1.11), p < 0.001

ref

1.15 (0.90, 1.45), p = 0.259

1.01 (0.76, 1.36), p = 0.923

1.73 (1.36, 2.20), p < 0.001

p < 0.001

  1. Data is presented with mean (SD) or number of participants (percentage)
  2. p < 0.05 indicate significant difference between or across groups
  3. * Crude model
  4. † Adjusted for age, gender, and race/ ethnicity
  5. ‡ Further adjusted for BMI, smoking status, systolic blood pressure on right arm, smoking status, drinking status, TCHO, HDL-c and HbA1c
  6. Abbreviations: ILSBPD: inter-leg systolic blood pressure difference; NHANES: National Health and Nutrition Examination Survey; BMI: body mass index; SBP: systolic blood pressure; TCHO: total cholesterol; HDL-c: high density lipoprotein cholesterol; HbA1c: glycated hemoglobin