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Table 2 Independent association of hypertension and depression with all-cause and CVD mortality

From: Association of hypertension and depression with mortality: an exploratory study with interaction and mediation models

 

Hypertension

Depression

Number of participants

Absent

Present

Absent

Present

17740

17412

32059

3093

All-cause mortality

 Events/Person-years

796/140881

2793/124127

3192/242520

397/22489

 Mortality ratesa

4.5 (4.1-4.9)

17.2 (15.9-18.4)

9.7 (9.0-10.4)

15.1 (13.0-17.2)

 Model 1

Reference

3.9 (3.5-4.3)

Reference

1.5 (1.3-1.7)

 Model 2

Reference

1.2 (1.1-1.3)

Reference

1.8 (1.6-2.1)

 Model 3

Reference

1.2 (1.0-1.3)

Reference

1.4 (1.2-1.7)

 PAF (95% CI), %

8.3 (1.9-14.8)

2.7 (1.4-4.0)

CVD mortality

 Events/Person-years

187/140881

901/124127

972/242520

116/22489

 Mortality ratesa

0.9 (0.7-1.1)

5.4 (4.8-6.0)

2.8 (2.5-3.1)

4.2 (3.2-5.1)

 Model 1

Reference

5.9 (4.8-7.3)

Reference

1.4 (1.1-1.7)

 Model 2

Reference

1.5 (1.2-1.9)

Reference

1.9 (1.6-2.4)

 Model 3

Reference

1.5 (1.1-2.1)

Reference

1.5 (1.2-2.0)

 PAF (95% CI), %

21.7 (8.8-34.6)

3.1 (0.5-5.7)

  1. Model 1 did not adjust any confounders. Model 2 was adjusted for age, gender, race/ethnicity, education, and income. Model 3 was adjusted for age, gender, race/ethnicity, education, income, obesity, diabetes, dyslipidemia, history of CVD, history of cancer, length of physical activity, smoking, alcohol use, antidepressant use, and substance use
  2. PAF Population attributable fraction, CVD Cardiovascular disease, CI Confidence interval
  3. aPer 1000-person years